As a consequence, the distance between enhancer and promoter is reduced ... Figure 2: Formation of loop domains by an insulator. The ability of insulators to confer transgenes position-independent ...

RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. Enhancers are regions of DNA that act as molecular switches for turning genes on or ...

One distinct feature of transcription factors is that they have DNA-binding domains that give them the ability to bind to specific sequences of DNA called enhancer or promoter sequences.

This allows the enhancers to physically interact with "promoters"—regulatory DNA regions located at the beginning of genes.