Our group is focused on understanding the role of endothelial and stem cells in heart and skeletal muscle diseases, metabolic regulation as well as in cancer. The major interest is in the endothelial ...

If insulin can’t get out of blood vessels, it can’t act in its target tissues. “Endothelial cells are full of insulin ...

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells ...

Adding engineered human blood vessel-forming cells to islet transplants boosted the survival of the insulin-producing cells ...

BSc in Pharmacy, University of Helsinki, 1997 MSc in Exercise physiology, University of Jyväskylä, 2001 PhD, University of Jyväskylä, 2008 Post doctoral research fellow, Prof. Kari Alitalo's group, ...

These studies focus on the role of the microvasculature in tissue damage. Endothelial cells generate 20-fold more of a unique form of acid sphingomyelinase (ASMase), termed Secretory ASMase, than any ...

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type ...

Insulin resistance primarily affects key metabolic cells, including those in skeletal muscle, adipose tissue, and the liver. Endothelial cells within blood vessels also express insulin receptors, and ...