Upon uptake, proteins and soluble components from the extracellular space pass through endosomes before fusing and/or maturing to form lysosomes. During the endosome–lysosome transition ...

The product of endosome–autophagosome fusion is known as an amphisome. The completed autophagosome or amphisome fuses with a lysosome, which supplies acid hydrolases. The enzymes in the ...

(6) Lysosomes directly take up mitochondria by the lysosomal membrane invagination. (7) Endosome/pre-lysosome directly ‘hit and run’ with mitochondria or MDV to form mitochondria-lysosome ...

More information: Marine Bretou et al, Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites ...

Materials marked for degradation are passed to late endosomes and eventually to lysosomes ... which plays a vital role in regulating endosome maturation. This gene encodes a deubiquitinating ...

Endocytosis and degradation of the membrane receptors in the lysosome controls the activation of intracellular signaling pathways ... US show that hepatocyte growth factor regulates endosome membrane ...