The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...

An intercellular signaling mechanism between adipocytes and hepatocytes could unlock new insights into metabolic disease.

The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

Inside cells, there exists an extensive system of canals known as the endoplasmic reticulum (ER), which consists of membrane-encased tubes that are partially broken down as needed—for instance ...

Our research group studies the mechanisms of protein trafficking and quality control at the endoplasmic reticulum (ER) in mammalian cells. A major focus of research is on the COPII protein machinery ...

Nwd1 deletion disrupts sarco/endoplasmic reticulum calcium ATPase (SERCA2) activity, which leads to heightened endoplasmic reticulum stress, contributing to metabolic dysfunction-associated ...

The Jokitalo group studies structure-function interplay of organelles in mammalian cells. Our main model organelle is the endoplasmic reticulum. We employ a wide range of basic biological techniques ...

The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...