The results showed that PAK5 overexpression increased PKM2 protein levels and activity, leading to enhanced glycolysis and endometriotic cell growth. Conversely, PAK5 knockdown reduced PKM2 levels ...

Endometriosis occurs when endometrial tissue, normally formed in the lining of the uterus, starts to grow outside the uterine cavity, creating endometriotic lesions. This can lead to painful ...