Many of our views of the pathogenesis of brain edema and intracranial hypertension have originated from work in the rat after portacaval anastomosis receiving an ammonia infusion. Although this ...

Pathogenesis –- literally how disease (pathos) begins (genesis) or develops –- is a broad, important area of research encompassing both basic and clinical sciences. Disease can arise from ...

Ornithine-aspartate stimulates muscle glutamine synthetase in experimental ALF and prevents the development of brain edema. [30] The role of amino acids in ammonia disposal in ALF deserves further ...