Signalling between Notch receptors and ligands influences many differentiation processes and cell-fate decisions during embryonic and postnatal development. Stem-cell maintenance, binary cell-fate ...

For example, Notch signaling singles out individual neural precursors from clusters of cells ... BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila. Nature ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

Genetic studies in model organisms, including Drosophila, have a rich history of fundamental insights in neuroscience, including the identification and functional dissection of genes important in ...

All main stocks (>5000 individual lines) of Drosophila melanogaster are housed within a 18 0 C/70%RH controlled room with a remote wireless monitoring and alarm service. The individual lab stock ...