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Trends in Genetics 22, 46–55 (2006). Argueso, J. L. et al. Double-strand breaks associated with repetitive DNA can reshape the genome. Proceedings of the Naitonal Academy of Sciences 105 ...
They can also be produced when DNA replication forks encounter DNA single-strand breaks or other types of lesion. They can occur at the termini of chromosomes due to defective metabolism of ...
Original DNA template - DNA is a double helix made of two complementary strands. Each strand can be used as a template to create a new DNA molecule. Free DNA nucleotides – needed to form the new ...
A DNA double helix is made of two strands running in opposite directions. Each strand is made of four bases -- A, T, C, and G -- that pair up in specific ways to form rungs along the strands.
But where and how does the famous double helix fit into chromosomes ... We've now zoomed in enough to see portions of the DNA strand. The DNA is wrapped around histones -- protein structures ...
DNA replication is the process by which the DNA molecule makes an exact copy of itself during cell division. The double helix unwinds, and each strand serves as a template for the synthesis of a new ...
Study reveals alpha-synuclein's role in enhancing DNA repair in melanoma, linking Parkinson's protein to cancer cell survival ...
Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that comprise the human genome. But where and how does the famous double helix fit into ...
“That’s the long-term vision anyway.’’ Balasubramanian and his team made an antibody that bound tightly to G-quadruplex structures, but not to traditional double-helix DNA, and found that it bound to ...
Recent efforts in our lab have focused on complexes mediating DNA double strand break (DSB) repair. These range from the Structure Maintenance of Chromosome Smc5/6 complex involved in rescue of ...
Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...