Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal ...

An antibody molecule consists of two heavy chains (approximately 50 kDa each) and two light chains (approximately 25 kDa each). These chains are interconnected by disulfide bonds, resulting in a ...

and the two heavy chains are likewise attached by a third disulfide bond. By these arrangements, each of the two arms of the antibody includes one light chain and one heavy chain, with the ...

The properties of the different IgG isotypes should be considered in developing therapeutic antibodies. To address this problem, antibody engineers introduced a serine-to-proline substitution that ...