An additional three cases had double trisomies as well as another abnormality (i.e., derivative chromosome or mosaicism), bringing the total to 57 cases (67.1%). Further delineation can be found ...

mFISH can be applied during interphase and metaphase. mFISH assays are indispensable for a precise description of derivative chromosomes identified in banding cytogenetics. Small supernumerary ...

Multicolor FISH (mFISH) assays are currently indispensable for a precise description of derivative chromosomes. Routine application of such techniques on human chromosomes started in 1996 with the ...

The first step in the development of such an assay was provided by the isolation and characterization of a set of 41 cosmid, P1 and PAC clones specific for all human subtelomeric chromosome ...