Semiconservative replication was not the only model of DNA replication proposed during the mid-1950s, however. In fact, two other prominent hypotheses were put also forth: conservative replication ...

During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights into viral replication mechanisms.

This new study provides definitive evidence about how these secondary DNA structures can pose physical barriers to DNA ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...

The effect of saccharin on the microbiome has received much attention, but its impact on pathogenic bacterial species is less ...

Chromosomes are the carriers of the genetic and epigenetic information and faithful chromosome replication is of fundamental importance for genome maintenance during normal cell proliferation. We ...

The team initially set out to study another replication machinery protein ... “This experiment is really the nail in the coffin of this model where everything is sitting stably on the DNA,” van Oijen ...

While scientists have long known the importance of helicase in DNA replication, "they did not know how DNA, helicases and ATP work together in a coordinated cycle to drive DNA unwinding," De ...

DNA is susceptible to damage caused by errors committed during replication and by environmental factors, such as radiation, oxidants, or alkylating agents. Repair reactions involve the excision of ...