During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

The first section of the book, Cellular DNA Replication, begins with an excellent overview of genome duplication by Thomas J. Kelly and Bruce Stillman, followed by chapters on specific steps in ...

During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...

Additionally, the scientists unexpectedly captured for the first time a detailed picture of how the "engine" driving the ...

Additionally, the scientists unexpectedly captured for the first time a detailed picture of how the "engine" driving the cellular replication machinery moves along DNA in human cells. Their ...

A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication. Cell lines ...