A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication. Cell lines ...

In their new study, the researchers studied the DNA replication patterns in early embryos. "We discovered differences in the replication mechanisms of maternal and paternal DNA during the initial ...

Deoxyribonucleic acid (DNA) replication is fundamental to life, yet the precise mechanics of how helicases unwind the genome for replication remain unclear. A recent study published in Nature used ...