New study reveals how DNA repair genes play a major role in Huntington's disease
A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in ...
Labroots1 天
Revealing the Role of DNA Repair Genes in Huntington's
Huntington's disease is a neurodegenerative disorder that is usually fatal about 15 to 20 years after a patient is diagnosed. It is known ... | Genetics And Genomics ...
How DNA's environment shapes smoking-related cancer risk
Cigarette smoke causes cancer primarily by damaging the DNA. A new study that mapped these damages has revealed that the way ...
Boosting autophagy in eggs may reduce DNA damage and reproductive complications
Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, ...
FierceBiotech1 天
Oligonucleotide stops gene expansion process that drives Huntington's disease: study
Less than a month after researchers unveiled that a “ticking DNA clock” is behind Huntington’s disease (HD), scientists have ...
devdiscourse1 天
Unmasking the Genetic Code Behind Breast Cancer Resistance
Researchers from TMC and NIBMG have uncovered key genomic factors contributing to hormone treatment resistance in breast cancer. The study identifies mutations in three genes, DNA repair deficiencies, ...
AlphaGalileo1 天
How the DNA’s Environment Shapes Smoking-Related Cancer Risk
Cigarette smoke causes cancer primarily by damaging the DNA. A new study that mapped the DNA damages caused by smoking, ...
BioWorld3 天
Targeting DEK to reduce replication stress restores HSC function in Fanconi anemia
Fanconi anemia (FA) is a rare genetic disorder characterized by defective DNA repair, leading to hematopoietic stem cell (HSC) dysfunction and bone marrow failure. Replication stress, which ...