The methylation of plasma cell-free DNA (cfDNA) has emerged as a valuable diagnostic and prognostic biomarker in various cancers including colorectal cancer (CRC). Currently, there are no biomarkers ...
Even with prostate-specific antigen testing, there is significant ... Highly sensitive and specific DNA-based assays like DNA methylation-specific PCR technology allow the detection of gene ...
often severely compromising test results. Image Credit: Roche Diagnostics The Digital LightCycler ® dPCR System is a new dPCR-based method for DNA methylation analysis. This method does not rely ...
DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...
To test in vitro performance ... Histone-based predictors were compared to DNA methylation-based predictors, with the study noting the impact of differences in sample size and dataset ...