DNA methylation is a fundamental epigenetic mechanism in which a methyl group ... WGBS consists of library preparation with bisulfite treatment, next-generation sequencing (NGS), and high throughput ...

Changes in DNA methylation patterns occur early during oncogenesis, and each type of cancer has its own methylomic signature. Technological advances in methylation sequencing, or methyl-seq, allow ...

Congenital heart disease (CHD) affects approximately 1% of live births. Thanks to surgical advancements, infants born with ...

The relationship between DNA methylation and gene expression is ... published in the journal Nature Genetics. Real-time DNA sequence analysis is made possible by a new technology called nanopore ...

Why are lemons sour? Delve into the genetic explanations behind the tartness of lemons and their production of citric acid.

The SPRQ chemistry brings three major benefits: 4x lower DNA input, 33% higher sequencing yield and more accurate direct methylation detection. With only 500 ng of DNA needed for a human whole genome, ...

The Twist NGS Methylation Detection System provides a robust, end-to-end sample preparation solution for identifying methylated regions in the human genome. Library preparation employs a unique, ...

Epigenetic clocks that quantify rates of aging from DNA methylation patterns across the genome have emerged as a potential biomarker for risk of age-related diseases, like Alzheimer’s disease (AD), ...

c) Programmable assembly of mobile DNA types carrying epi-bits. d) Parallel printing via DNMT1-guided catalysis to selectively write epi-bits. e) Nanopore sequencing of modified templates and ...