Mutations can be grouped into two main categories based on where they occur: somatic mutations and germ-line mutations ... that alter longer stretches of DNA (ranging from multiple genes up ...

A single DNA nucleotide, the base unit of the human genome, is a tiny, tiny thing. Each one is made up of only 30 atoms (plus or minus a few, depending on the base), making it much too small to be ...

and the smaller genomic DNA fragments were subcloned into vectors to generate a BAC-derived shotgun library. The inserts were sequenced using primers matching the vector sequence flanking the ...