The basic pattern of genomic DNA methylation is established at the time of embryo implantation through a wave of de novo methylation, but CpG islands are protected through a mechanism that ...

Liver TET1 was found to promote metabolic dysfunction-associated steatotic liver disease (MASLD) by regulating CD36 ...

These modifications, which include DNA methylation ... For instance, abnormal CpG island hypermethylation is frequently observed in cancers and is often linked to tumor suppressor genes.