Crick and Watson were trying to build a 3D model of the DNA molecule ... This showed that DNA had a helix shape. Without her knowledge, one of her colleagues showed the picture to James Watson.

This technique, called volumetric DNA microscopy, creates a 3D image of an entire organism ... DNA image of a zebrafish embryo, a common model organism for studying development and neurobiology.

In fact, Watson and Crick were worried that they would be "scooped" by Pauling, who proposed a different model for the three-dimensional structure of DNA just months before they did. In the end ...

Later it was found that the sugar in nucleic acid can be ribose or deoxyribose, giving two forms: RNA and DNA ... model, so that matching base pairs interlocked in the middle of the double helix ...

By tagging each DNA or RNA molecule and allowing neighboring tags to interact, the technique constructs a molecular network that encodes their relative positions, creating a spatial map of genetic ...