Genotoxic stressors, including oxidative stress, inflammation, and environmental factors are closely intertwined processes that significantly contribute to ...

Mar. 16, 2023 — Researchers have now encapsulated the young field of nucleolar DNA damage response (DDR) pathways. A new review highlights six mechanisms by which cells repair DNA damage. By ...

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response ... cells react to DNA damage could lead to ...

Results of a study led by the Vall d'Hebron Institute of Oncology (VHIO) support the feasibility of using RAD51 testing to ...

This is important because some forms of cell death are unnoticed by the immune system, while others trigger an immune response ... "The DNA inside our cells is constantly experiencing damage ...

This extension builds on a 2024 agreement to define and discover biomarkers within the DNA damage response (DDR) biological space to predict the clinical benefit of one or more drugs in Debiopharm ...

For this reason, they are at greater risk of accumulating damage and must develop alternative repair pathways to avoid dysfunction. Scientists do not understand how neuronal DNA damage is ...

Spending enough time in the sun without adequate protection can leave us looking and presumably feeling like a lobster ready for the plate.