在人类和动物实验中,多巴胺水平的改变与攻击性行为的变化密切相关。例如,抗精神病药物通过阻断多巴胺D2受体(D2 receptor),显著降低了患者的攻击性行为,但也引发了关于其是否通过镇静作用间接抑制攻击的争议。此外,某些刺激多巴胺释放的药物 ...
1998). These five subtypes have been grouped into two different classes based on pharmacology and biochemistry: the D1-like and the D2-like receptors. The D1-like receptors, D1 and D5, mediate ...
Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...
Recently, timed-release bromocriptine (Cycloset), a sympatholytic dopamine D 2 receptor agonist, has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of type 2 diabetes.
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