Yet for some infections, the antibody response may not be enough. In such cases, vaccines can also be developed to promote cytotoxic T cell activity, or perhaps a combination of both antibody and ...

Research teams led by Wolfgang Kastenmüller and Georg Gasteiger have used advanced microscopy techniques to study how T-cells—key players in the immune system—activate and multiply during ...

In this cross-sectional study, researchers explored immune activation as a possible mechanism for this seemingly paradoxical response to HIV infection. CD4-cell counts and T-cell activation levels ...

Cytotoxic T cells ... that the cellular architecture of T cells influences which of these two functions the cells adopt when they undergo pathogen-induced activation. As well as improving our ...

Pluri has announced the issuance of a patent by the US Patent and Trademark Office (USPTO) for its immune cell expansion ...

Apoptosis can also be triggered externally using receptors on the cell membrane to which a cytotoxic T cell connects. Using these intrinsic and extrinsic apoptosis pathways cells generally either ...

In certain cancers, QRICH1 could be used to increase T-cell activation to fight and kill off cancer cells more effectively. In autoimmune diseases and certain blood cancers, including leukemia and ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

Preclinical data further support the potential of dual-antigen and TGF-β-directed vaccines to reshape the tumor microenvironment and drive anti-tumor immunity NEW YORK, April 25, 2025 (GLOBE NEWSWIRE) ...

an immune barrier is in place that mitigates graft-vs-host disease by preventing massive T-cell proliferation while still allowing for T-cell activation.