which helps maintain the integrity of DNA by removing uracil residues that can arise from cytosine deamination or misincorporation during DNA replication. The detection and analysis of UDG ...

This reaction, deamination, is about twice as likely to happen when a cytosine is chemically tagged by the addition of a molecule known as a methyl group to create 5-methylcytosine, which occurs ...

Since the two sequence alterations in the Indian family, Q155X and 483C→T, are both cytosine to thymidine mutations, cytosine deamination as the mutational mechanism cannot be ruled out a priori.