为解决卵巢癌治疗难题，东京大学的研究人员开展了关于 PLK1 和 WEE1 抑制剂治疗卵巢癌的研究，发现 Cyclin E1 过表达可预测抑制剂疗效，为卵巢癌个性化治疗提供策略。 卵巢癌，作为妇科领域的 “夺命杀手”，一直让医学界头疼不已。上皮性卵巢癌死亡率极高 ...

WILMINGTON, DE — NiKang Therapeutics® Inc. has achieved a pivotal step in the development of its first-in-class CDK2 degrader ...

Proxygen GmbH has divulged molecular glue degraders comprising a cullin-ring E3 ligase (CRL)-binding moiety acting as cyclin-dependent kinase 12 (CDK12)/cyclin K degradation inducers reported to be ...

γ-herpesvirus genomes encode an abundance of homologues of cellular factors, including cyclin and Bcl-2. These viral homologues differ from their cellular counterparts in that the viral proteins ...

A "pocket" on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Two studies by researchers at the University of Konstanz ...

VERITAC-2 achieved its primary endpoint in the estrogen receptor 1-mutant population, demonstrating statistically significant and clinically meaningful ...