Affected children are born with café-au-lait spots and sometimes Lisch nodules. During adolescence and young adulthood, more ...

Among these tumors are cutaneous neurofibromas, benign tumors that grow from nerve terminals in the skin. Current treatment to reduce tumor growth in patients is limited to surgery, which can lead ...

These plexiform neurofibromas can be deep and close to ... And they can also be very close to the skin, which we call cutaneous nerve fibromas, and they cannot only be abnormal in shape so that ...

Patients with classic NF1 including the presence of cutaneous neurofibromas or Lisch nodules, as no genetic heterogeneity demonstrated so far associated with this phenotype. The NF1-only by NGS ...