Consider the repeating unit that forms the building block of the colon — the crypt 3. Within each crypt is a large population of differentiated cells with little or no proliferative capacity ...

New research describes the early steps of colorectal tumor formation and lays a foundation for improving ... This was followed by the appearance of precancerous cells at the top and bottom of the ...

An adaptation of the Vogelstein adenoma:carcinoma sequence. The acquisition of a mutation (or 'hit') in a stem cell within a crypt results in dysplastic progeny and leads to the entire crypt ...

"Colorectal cancer is very ... Without those stem cells, the crypt cells can't regenerate. To survive, the structure can ...

In a mouse with a functioning stem cell niche, the large intestine consists of numerous villi and crypts. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases ...

An IBEC-led study describes the development of an innovative method to control the formation of crypt-like structures ... in detail key processes such as cell regeneration or changes associated ...