New research describes the early steps of colorectal tumor formation and lays a foundation for improving diagnosis and treatment ... I don't necessarily think about normal stem cells dying when colon ...

Figure 5: Telomere dysfunction peaks at the adenoma-carcinoma transition in human colorectal carcinogenesis. Whole-mount staining/analysis of micro- and macroadenomas. The complete small and large ...

This review discusses some pros and cons of risk evaluation technologies in the colorectal tract by ... Any polyp 4 CIMP negative, MSS Adenoma-carcinoma sequence 5 (Lynch syndrome) CIMP negative ...

Colorectal cancer is an excellent example of the complex multistage process of carcinogenesis. Most colorectal cancers develop from adenomas (benign tumours also called polyps) in what is often ...

Nat Clin Pract Gastroenterol Hepatol. 2006;3(5):267-274. An adaptation of the Vogelstein adenoma:carcinoma sequence. The acquisition of a mutation (or 'hit') in a stem cell within a crypt ...

Restrictions apply.* Cologuard detects 92 percent of colorectal cancers with 87 percent specificity. *Cologuard is not for high-risk individuals, including those with a history of colorectal cancer ...