Chronic myeloid (or myelogenous) leukaemia (CML), also known as chronic granulocytic leukaemia, is a cancer of the white blood cells. It is characterized by the increased and unregulated growth of ...
The chimeric BCR–ABL oncoprotein is the molecular hallmark of chronic myelogenous leukemia (CML). BCR–ABL contains nuclear import and export signals but it is localized only in the cytoplasm ...
Melvin Mann, diagnosed with chronic myeloid leukemia in 1994, participated in a clinical trial for Imatinib that extended his ...
白血病干细胞中获得性miR-142缺失与慢性髓性白血病母细胞危象相关。在这里,作者表明T细胞中获得性miR-142缺陷进一步使白血病干细胞逃避免疫监视并支持疾病生长。
Researchers are exploring new treatment options for chronic myeloid leukemia (CML). Many treatments that have recently been studied or are currently under investigation are targeted therapy drugs.
Triplet Regimen Yields Promising Response in Advanced-Phase Chronic Myeloid Leukemia Sep. 17, 2024 — According to new research, 80% of patients with previously untreated or relapsed/refractory ...
Immune cells in the bone marrow microenvironment of AML patients are key in distinguishing a response to immunotherapy.
He was first diagnosed with Chronic Myeloid Leukaemia in 2013, aged 19 and relapsed after treatment. Whilst isolated in a ...
An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.
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