Structural variation in the genome can directly or ... reference assembly should be that it encompasses the longest chromosomal sequences, including polymorphic regions that might be absent ...

More recently, both aneuploidy and chromosomal translocations ... Recent analysis of the structural level — specifically CNVs — has revealed an additional source of variation, and this has ...

The work opens the door to studying and predicting the role of structural variation in disease. Structural variation is a change in the structure of an organism's genome, such as deletions, ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK Leibniz Institute (IPK) and the Karlsruhe Institute of Technology (KIT) has ...

Results prove that inversions can be generated in plants without causing further unwanted changes in the expression of genetic information.

The Layer Lab studies they ways in which genetic variation affects human health by developing computational genomics tools to analyze population-scale datasets. They are particularly interested in ...

They also constructed a comprehensive genomic variation map by resequencing 177 celery samples. This study was published in Plant Biotechnology Journal. Through phylogenetic, population structure ...