Understanding the material basis of adaptive evolution has been a central goal in biology dating back to at least the time of ...

Scientists report adaptive divergence in cryptic color pattern is underlain by two distinct, complex chromosomal rearrangements, where millions of bases of DNA were flipped backwards and moved from ...

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown ...

Complex DNA-breakage events such as chromosomal shattering, followed by genome rearrangement, DNA repair, and end-to-end ligation, ultimately result in the formation of ecDNAs (Panel B).

Through this approach, we aim to understand how faithful and efficient chromosomal DNA replication is achieved under normal conditions and, conversely, how the replication machinery is affected by and ...

However, characterizing chromosomal rearrangements with commonly tried DNA sequencing methods has been difficult. Many organisms, including humans, are diploid, meaning they have two sets of ...

Genetic fingerprint: A map of inherited biological genes that identifies an individual and distinguishes them from others. It consists of biological traits or a genetic profile of non-coding sites in ...

However, characterizing chromosomal rearrangements with commonly tried DNA sequencing methods has been difficult. Many organisms, including humans, are diploid, meaning they have two sets of ...