The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK Leibniz Institute (IPK) and the Karlsruhe Institute of Technology (KIT) has ...

To do so, they planned to stabilize proteins at their chromatin binding locations and use nucleic acid hybridization to fish out specific DNA sequences along with the bound proteins. By using enzymes ...

Various molecules called chromatin remodelers provide the mechanism ... 40 base pairs inside the nucleosome, from which location it pumps DNA around the histone-octamer surface.

New AI model takes minutes rather than days to predict how a specific DNA sequence will arrange itself in the cell nucleus.

Chromatin immunoprecipitation (ChIP ... of enriched fragments has proven a more effective means for determining locations of DNA-binding proteins along the genome in an unbiased manner.