Statins lower plasma cholesterol by upregulating LDL receptor gene expression and are consequently relatively ineffective in homozygous familial hypercholesterolemia (HoFH). The standard treatment ...

Cholesterol guidelines call FH screening reasonable for children and adolescents with a family history of either early ...

Scientists have discovered a potential new treatment for familial hypercholesterolemia, inspired by signs seen in the Mona ...

But others are predisposed to high cholesterol from a young age, and it has little to do with their lifestyle. These people have a genetic condition called familial hypercholesterolemia ...

Very aggressive management of LDL cholesterol, including with apheresis, is required to improve the prognosis. Patients with homozygous familial hypercholesterolemia show reduced or absent ...