The structure of carbohydrates—hexoses to be precise—posed one of the earliest chemical mysteries. Emil Fischer, a grandfather of chemical biologists, relied on phenyl hydrazine to elucidate ...

Protein glycosylation is a fundamental biological ... scientists from Fudan University developed a chemical ligation-based glycopeptide enrichment strategy called HG-TCs. This method uses advanced ...

Protein glycosylation is a fundamental biological ... scientists from Fudan University developed a chemical ligation-based glycopeptide enrichment strategy called HG-TCs. This method uses advanced ...

However, due to their non-DNA-encoded nature, glycans are much more challenging to study than other biomolecules. The GlycoTrackers team has developed a set of chemical “Precision Tools” that allow ...

leading a research group that seeks to develop bioorthogonal chemical reporters to study posttranslational modifications, specifically protein glycosylation and lactylation. A key aspect of his ...