在此，研究人员通过共表达末端连接（EJ）机制和靶向核酸内切酶，在人类细胞中构建 mtDNA 缺失。利用线粒体末端连接（mito-EJ）和线粒体 ScaI（mito-ScaI），研究人员生成了一组克隆细胞系，这些细胞系携带约 3.5kb 的 mtDNA 缺失，涵盖完整的异质性谱。 对这些细胞 ...

Interphase The cell spends most of its life in this phase. The DNA in chromosomes copies itself ready for mitosis. Prophase The DNA in chromosomes and their copies condenses to become more visible.

Microscopes are needed to study cells in detail. Cell division - AQA Chromosomes carry genetic information in a molecule called DNA. A type of cell division called mitosis ensures that when a cell ...

In addition, the authors discovered that mito + cells could survive and resist T cell exhaustion within the tumor ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...