Cefepime is a β-lactam antibiotic that is cleared through the kidneys. Elimination of cefepime is considerably delayed in patients with impaired renal function, and cefepime has been reported to ...

Current guidelines recommend that children with acute pyelonephritis are initially treated with a parenteral third-generation cephalosporin such as ceftriaxone, and then oral antibiotics.

No cases of neutropenia were reported for the 121 courses of antimicrobials other than cefepime. Among the 13 courses of cefepime therapy, 8 resulted in neutropenia after an average of 25 days of ...