The authors did, however, show that numbers of affinity-matured CD27 + IgD − immunoglobulin-class-switched memory B cells were higher in patients with no response or a moderate response than in ...

Research by Oflazoglu and colleagues now suggests that CD27–CD70 blockade could be a promising therapeutic strategy for autoimmune and autoinflammatory disorders. In addition, because the ...

At the time of B cell recovery, the IgD +, CD27+ memory B cell subset was significantly larger in the nonresponder group. Within the group of 12 responders, 6 patients experienced an early relapse ...