Caspase-3 is a prototypical group II effector caspase that can be activated by both the receptor and mitochondria-mediated pathways. Mice deficient in caspase-3 (caspase-3 −/−) have defective ...

Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark of apoptosis initiation—with fluorescent dyes. Researchers often perform multiplex caspase assays ...