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可视化细胞死亡过程中钙蛋白酶 - 1(Calpain-1)的激活及其通过化学 ...
为探究 Calpain-1 在细胞焦亡中的作用及开发检测工具,研究人员利用 HyCoSuL 方法设计了 Calpain-1 特异性工具,发现其可与焦亡标记物共定位并能直接切割 GSDMD,为解析蛋白酶在细胞死亡中的作用提供了平台。 钙蛋白酶 - 1(Calpain-1)是一种依赖钙的半胱氨酸蛋白酶 ...
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