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New enzyme discovery offers hope for millions of diabetes patientsCoenzyme A (CoA), already known for its metabolic roles ... selectively nitrosylating target proteins such as the insulin receptor and its substrates. Interestingly, the researchers discovered ...
The structure of yeast Esa1 suggests that different families of histone acetyltransferases employ similar mechanisms of substrate binding ... Figure 1: A common mode of CoA binding in the Gcn5 ...
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