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PLZF? CD4? T 细胞经 IL-15/IL-15Rα 信号通路调控哮喘免疫耐受新机制
在免疫系统中,免疫耐受的失衡是过敏性哮喘的关键致病因素。不同类型的细胞参与维持免疫耐受,其中 CD4? CD44?记忆 T 细胞与免疫耐受关系密切,而组织驻留记忆 T(TRM)细胞又是 CD4? CD44?记忆 T 细胞的重要亚型。不过,TRM 细胞在哮喘免疫耐受中的作用以及其受 ...
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