近期，宁夏医科大学基础医学院的 Liangying Zhang、Kun Xiao 等研究人员在《Scientific Reports》期刊上发表了题为 “SOCS2 inhibits the tumorigenesis of GISTs and increases the sensitivity of GISTs to imatinib by suppression of KIT ...

With this in mind, the authors aimed to redesign imatinib, focusing its specificity on C-Kit (also known as KIT) kinase inhibition (the therapeutic target for GIST) while reducing its effect on ...