It is likely that myosin II is regulated by changes in integrin signalling mediated by a feedback loop that connects adhesion, contractility and signalling through Rho GTPases. Cell migration ...

then a measurement of tether force on a cytoskeletally supported region of a cell (where Eqn 1 applies) and a bleb (where Eqn 2 applies) can be use to calculate the adhesion energy: ...