Top-down mass spectrometry offers the ability to sequence intact proteins—post-translational modifications and all—but is not yet a high-throughput method. As the well-established 'bottom-up' ...

A multiplex, mass spectrometry-based quantitative clinical chemistry proteomics (qCCP) test for cardiovascular assessment has been developed, analytically validated, implemented and scaled up for a ...

Our laboratory’s expertise is in the development and application of direct mass spectrometry technologies for tissue analysis and disease detection. Our research projects are focused on the ...