Patients who fail to respond to methotrexate monotherapy usually improve less following the addition of another nonbiologic DMARD than a biologic one. 10 In the BeSt study, 10 this step-up DMARD ...

Studies have shown nonbiologic DMARD combination therapy results in a larger number of responses than methotrexate monotherapy does. Biologic response modifiers target molecules or immune cells ...

Despite their differences, many people try both treatments. Your doctor will likely start you on a DMARD and move to a biologic if it doesn't work. Navigating so many options can be tricky but it ...

You may need to take more than one type of DMARD to keep your rheumatoid arthritis in check. If traditional RA drugs don't help, your doctor may prescribe you a biologic. These drugs target ...

Switching among biologic therapies is common practice in patients with rheumatoid arthritis who have an inadequate response or intolerable adverse events. Evidence from observational studies and ...