Biliary tract cancer is a rare adenocarcinoma that occurs in a bile duct, often causing jaundice, pruritus and weight loss. The lesion may be papillary or flat and ulcerated. The tumour is often ...

Background: The presence of infective microorganisms in the bilio-pancreatic tract is believed to be important in both the onset and outcome of acute biliary pancreatitis. In this study ...

Ceramide metabolism has garnered increasing attention in liver diseases, but its role in cholestatic liver injury remains unclear. Here the authors show that targeting ACER3, a ceramidase ...

IgG4-related disease is an increasingly recognized fibroinflammatory condition with protean manifestations. The disorder is ...

Circulating tumor DNA may be a prognostic biomarker for relapse and early recurrence detection in resected early-stage biliary tract cancer. Among patients with curatively resected early-stage biliary ...

The results of a clinical trial led by researchers at the University of Arizona Health Sciences and published in the Journal of Clinical Oncology show that chemotherapy combining three different ...

But new molecular testing, available in Ottawa and across Canada, is offering patients some hope. ...

Eisai has filed for approval in Japan for tasurgratinib, its small-molecule fibroblast growth factor (FGF) receptor inhibitor, as a treatment for biliary tract cancers with FGFR2 gene fusion ...

MSD’s PD-1 inhibitor Keytruda has been approved by the FDA as a treatment for locally advanced unresectable or metastatic biliary tract cancer (BTC) in combination with chemotherapy, the first ...

Objectives: After completion of this article, the reader should understand (1) the theories of causation of biliary atresia, (2), the data supporting involvement of viral infection in pathogenesis ...