Basophils, a type of immune cell that makes up less than 1% of white blood cells, have recently emerged as critical players ...

Basophils trigger a cytokine cascade that improves antitumor immunity in mice, offering potential targets for cancer immunotherapy. “The results remind us: Don’t forget the basophil,” said study ...

These include the accumulation of potentially beneficial IgE–anti-IgE immune complexes and the downregulation of the high-affinity IgE Fc receptors (FcɛRI) on basophils and mast cells.