which usually develop into white blood cells called lymphocytes. In B-PLL, B-lymphocytes grow and divide excessively, crowding out healthy cells. B-PLL has a high rate of recurrence, and the ...

Cells treated with ibrutinib and acalabrutinib each had a unique set of 13 m/z signals, which opens up the possibility of studying these metabolites as biomarkers of therapeutic response.

Amplified CD56+CD3− cells had spontaneous and anti-B cell-activating factor receptor mAb-stimulated ADCC activity against allogeneic ALL cells, which could be further enhanced by IL-15.

The transcription factor interferon regulatory factor 5 (IRF5) has previously been implicated in systemic lupus erythematosus (SLE) development, but its precise role in this process is unknown.

Pfizer’s Takeda-partnered blood cancer drug Adcetris (brentuximab vedotin) has been approved by the US Food and Drug ...

To begin, lymphocytes are a type of white blood cell that helps the body fight infection. There are two main types of lymphocytes: B-lymphocytes and T-lymphocytes. Of these, there are two types of ...

Introduction: A unique feature of chronic lymphocytic leukemia (CLL) is the increased number of circulating T cells preventing malignant B cells from undergoing apoptosis. Dysregulated expression of ...

Northwestern Medicine scientists have uncovered a key pathway controlling tumor growth in B-cell lymphomas, according to a study published in the Journal of Clinical Investigation.

Each lymphocyte produces its own specific receptor that corresponds to a specific antigen. When a lymphocyte encounters that antigen it multiplies, creating large numbers of identical lymphocytes ...