Other recent evidence points to a role for dendritic cells (DCs) in antigen presentation to primary B cells. It has been reported that DCs pulsed with soluble antigen can prime naïve B cells in T ...

Cellular and Molecular Immunology 8, 296–304 doi:10.1038/cmi.2011.2 ...

Researchers at Moffitt Cancer Center have found that tapping into the body's own immune system and activating a type of immune cell known as B ... cells that have infiltrated the tumor, known ...

Breast cancer is becoming increasingly treatable, but in some cases the disease can resurface even decades after a patient ...

Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce ...

Tertiary lymphoid structures (TLS) are increasingly recognized to have roles in cancer. Within tumor microenvironments (TME), TLS can arise as ectopic lymphoid organs containing aggregates of ...

In many cases, tumors use different traits and channels to go undetected by the immune system. Immunotherapy redirects the immune system to recognize and target the tumor. Many treatments are aimed at ...