against earlier classes of antifungals. Olorofim, F2G’s orotomide currently in clinical development, has shown promising in vitro and in vivo activity against azole-resistant A. fumigatus and ...

While occurrence and risks of azole antifungals in wastewater and meat industry have been studied, their presence in surface water and potential threats to water quality are underexplored. This ...

Potent inhibitors of both CYP3A4 and P-gp include azole antifungals (e.g., ketoconazole, itraconazole, voriconazole and posaconazole) and protease inhibitors (e.g., atanazavir). INR: International ...