In addition, low-grade astrocytomas with high VRK2 protein levels also had better prognosis but this association ... was similar to that observed in astrocytoma biopsies. All cell lines express ...

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Methods and results: VRK1 and VRK2 (Vaccinia-related kinase-1, -2) expression, as well as proliferation markers, were determined in a tissue microarray containing 105 primary astrocytoma biopsies.